Role and regulation of the forkhead transcription factors FOXO3a and FOXM1 in carcinogenesis and drug resistance

The FOXO3a and FOXM1 forkhead transcription factors are key players in cancer initiation, progression, and drug resistance. Recent research shows that FOXM1 is a direct transcriptional target of FOXO3a, a vital downstream effector of the PI3K-AKT-FOXO signaling cascade. In addition, FOXM1 and FOXO3a...

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Detalles Bibliográficos
Autores principales: Gomes, Ana R., Zhao, Fung, Lam, Eric W.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sun Yat-sen University Cancer Center 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845605/
https://www.ncbi.nlm.nih.gov/pubmed/23706767
http://dx.doi.org/10.5732/cjc.012.10277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845605/
https://www.ncbi.nlm.nih.gov/pubmed/23706767
http://dx.doi.org/10.5732/cjc.012.10277

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