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In Astrocytes the Accumulation of the Immunity-Related GTPases Irga6 and Irgb6 at the Vacuole of Toxoplasma gondii Is Dependent on the Parasite Virulence

Toxoplasma gondii is an obligate intracellular protozoan parasite responsible for a common infection of the central nervous system. Interferon (IFN)γ is the key cytokine of host defence against T. gondii. However, T. gondii strains differ in virulence and T. gondii factors determining virulence are...

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Detalles Bibliográficos
Autores principales: Lubitz, Felix P., Degrandi, Daniel, Pfeffer, Klaus, Mausberg, Anne K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845628/
https://www.ncbi.nlm.nih.gov/pubmed/24324375
http://dx.doi.org/10.1155/2013/480231