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Evaluating the Fitness Cost of Protein Expression in Saccharomyces cerevisiae

Protein metabolism is one of the most costly processes in the cell and is therefore expected to be under the effective control of natural selection. We stimulated yeast strains to overexpress each single gene product to approximately 1% of the total protein content. Consistent with previous reports,...

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Detalles Bibliográficos
Autores principales: Tomala, Katarzyna, Korona, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845635/
https://www.ncbi.nlm.nih.gov/pubmed/24128940
http://dx.doi.org/10.1093/gbe/evt154