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In Vitro Manganese Exposure Disrupts MAPK Signaling Pathways in Striatal and Hippocampal Slices from Immature Rats

The molecular mechanisms mediating manganese (Mn)-induced neurotoxicity, particularly in the immature central nervous system, have yet to be completely understood. In this study, we investigated whether mitogen-activated protein kinases (MAPKs) and tyrosine hydroxylase (TH) could represent potential...

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Detalles Bibliográficos
Autores principales: Peres, Tanara Vieira, Pedro, Daniela Zótico, de Cordova, Fabiano Mendes, Lopes, Mark William, Gonçalves, Filipe Marques, Mendes-de-Aguiar, Cláudia Beatriz Nedel, Walz, Roger, Farina, Marcelo, Aschner, Michael, Leal, Rodrigo Bainy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845707/
https://www.ncbi.nlm.nih.gov/pubmed/24324973
http://dx.doi.org/10.1155/2013/769295