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Atorvastatin Treatment of Rats with Ischemia-Reperfusion Injury Improves Adipose-Derived Mesenchymal Stem Cell Migration and Survival via the SDF-1α/CXCR-4 Axis

BACKGROUND: Adipose-derived mesenchymal stem cells (ASCs) transplantation is a promising approach for myocardium repair. Promotion of ASCs migration and survival is the key for improving ASCs efficiency. SDF-1α is a critical factor responsible for ASCs migration and survival. Atorvastatin (Ator) is...

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Detalles Bibliográficos
Autores principales: Cai, Anping, Qiu, Ruofeng, Li, Liwen, Zheng, Dongdan, Dong, Yugang, Yu, Danqing, Huang, Yuli, Rao, Shaoqi, Zhou, Yingling, Mai, Weiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846471/
https://www.ncbi.nlm.nih.gov/pubmed/24312447
http://dx.doi.org/10.1371/journal.pone.0079100