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DNase γ Is the Effector Endonuclease for Internucleosomal DNA Fragmentation in Necrosis
Apoptosis and necrosis, two major forms of cell death, can be distinguished morphologically and biochemically. Internucleosomal DNA fragmentation (INDF) is a biochemical hallmark of apoptosis, and caspase-activated DNase (CAD), also known as DNA fragmentation factor 40 kDa (DFF40), is one of the maj...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846476/ https://www.ncbi.nlm.nih.gov/pubmed/24312463 http://dx.doi.org/10.1371/journal.pone.0080223 |