Cargando…

Computational Prediction of Broadly Neutralizing HIV-1 Antibody Epitopes from Neutralization Activity Data

Broadly neutralizing monoclonal antibodies effective against the majority of circulating isolates of HIV-1 have been isolated from a small number of infected individuals. Definition of the conformational epitopes on the HIV spike to which these antibodies bind is of great value in defining targets f...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferguson, Andrew L., Falkowska, Emilia, Walker, Laura M., Seaman, Michael S., Burton, Dennis R., Chakraborty, Arup K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846483/
https://www.ncbi.nlm.nih.gov/pubmed/24312481
http://dx.doi.org/10.1371/journal.pone.0080562