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Computational Prediction of Broadly Neutralizing HIV-1 Antibody Epitopes from Neutralization Activity Data
Broadly neutralizing monoclonal antibodies effective against the majority of circulating isolates of HIV-1 have been isolated from a small number of infected individuals. Definition of the conformational epitopes on the HIV spike to which these antibodies bind is of great value in defining targets f...
Autores principales: | Ferguson, Andrew L., Falkowska, Emilia, Walker, Laura M., Seaman, Michael S., Burton, Dennis R., Chakraborty, Arup K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846483/ https://www.ncbi.nlm.nih.gov/pubmed/24312481 http://dx.doi.org/10.1371/journal.pone.0080562 |
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