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BAP1 deficiency causes loss of melanocytic cell identity in uveal melanoma
BACKGROUND: Uveal melanoma is a highly aggressive cancer with a strong propensity for metastasis, yet little is known about the biological mechanisms underlying this metastatic potential. We recently showed that most metastasizing uveal melanomas, which exhibit a class 2 gene expression profile, con...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846494/ https://www.ncbi.nlm.nih.gov/pubmed/23915344 http://dx.doi.org/10.1186/1471-2407-13-371 |