Fine mapping of V(D)J recombinase mediated rearrangements in human lymphoid malignancies

BACKGROUND: Lymphocytes achieve diversity in antigen recognition in part by rearranging genomic DNA at loci encoding antibodies and cell surface receptors. The process, termed V(D)J recombination, juxtaposes modular coding sequences for antigen binding. Erroneous recombination events causing chromos...

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Detalles Bibliográficos
Autores principales: Halper-Stromberg, Eitan, Steranka, Jared, Giraldo-Castillo, Nicolas, Fuller, Timothy, Desiderio, Stephen, Burns, Kathleen H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846541/
https://www.ncbi.nlm.nih.gov/pubmed/23957733
http://dx.doi.org/10.1186/1471-2164-14-565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846541/
https://www.ncbi.nlm.nih.gov/pubmed/23957733
http://dx.doi.org/10.1186/1471-2164-14-565

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