Sex differences in the prognostic significance of KRAS codons 12 and 13, and BRAF mutations in colorectal cancer: a cohort study

BACKGROUND: Activating KRAS and BRAF mutations predict unresponsiveness to EGFR-targeting therapies in colorectal cancer (CRC), but their prognostic value needs further validation. In this study, we investigated the impact of KRAS codons 12 and 13, and BRAF mutations on survival from CRC, overall an...

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Detalles Bibliográficos
Autores principales: Wangefjord, Sakarias, Sundström, Magnus, Zendehrokh, Nooreldin, Lindquist, Kajsa Ericson, Nodin, Björn, Jirström, Karin, Eberhard, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846575/
https://www.ncbi.nlm.nih.gov/pubmed/24020794
http://dx.doi.org/10.1186/2042-6410-4-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846575/
https://www.ncbi.nlm.nih.gov/pubmed/24020794
http://dx.doi.org/10.1186/2042-6410-4-17

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