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Sex differences in the prognostic significance of KRAS codons 12 and 13, and BRAF mutations in colorectal cancer: a cohort study
BACKGROUND: Activating KRAS and BRAF mutations predict unresponsiveness to EGFR-targeting therapies in colorectal cancer (CRC), but their prognostic value needs further validation. In this study, we investigated the impact of KRAS codons 12 and 13, and BRAF mutations on survival from CRC, overall an...
Autores principales: | Wangefjord, Sakarias, Sundström, Magnus, Zendehrokh, Nooreldin, Lindquist, Kajsa Ericson, Nodin, Björn, Jirström, Karin, Eberhard, Jakob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846575/ https://www.ncbi.nlm.nih.gov/pubmed/24020794 http://dx.doi.org/10.1186/2042-6410-4-17 |
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