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Comprehensive characterization of erythroid-specific enhancers in the genomic regions of human Krüppel-like factors

BACKGROUND: Mapping of DNase I hypersensitive sites (DHSs) is a powerful tool to experimentally identify cis-regulatory elements (CREs). Among CREs, enhancers are abundant and predominantly act in driving cell-specific gene expression. Krüppel-like factors (KLFs) are a family of eukaryotic transcrip...

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Detalles Bibliográficos
Autores principales: Xiong, Qian, Zhang, Zhaojun, Chang, Kai-Hsin, Qu, Hongzhu, Wang, Hai, Qi, Heyuan, Li, Yajuan, Ruan, Xiuyan, Yang, Yaran, Yang, Yadong, Li, Yanming, Sandstrom, Richard, Sabo, Peter J, Li, Qiliang, Stamatoyannopoulos, George, Stamatoyannopoulos, John A, Fang, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846580/
https://www.ncbi.nlm.nih.gov/pubmed/23985037
http://dx.doi.org/10.1186/1471-2164-14-587