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Bacterial artificial chromosome derived simian varicella virus is pathogenic in vivo

BACKGROUND: Varicella zoster virus (VZV) is a neurotropic alphaherpesvirus that infects humans and results in chickenpox and herpes zoster. A number of VZV genes remain functionally uncharacterized and since VZV is an obligate human pathogen, rigorous evaluation of VZV mutants in vivo remains challe...

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Detalles Bibliográficos
Autores principales: Meyer, Christine, Dewane, Jesse, Haberthur, Kristen, Engelmann, Flora, Arnold, Nicole, Gray, Wayne, Messaoudi, Ilhem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846606/
https://www.ncbi.nlm.nih.gov/pubmed/24010815
http://dx.doi.org/10.1186/1743-422X-10-278