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miR-150 Promotes Human Breast Cancer Growth and Malignant Behavior by Targeting the Pro-Apoptotic Purinergic P2X(7) Receptor
The P2X(7) receptor regulates cell growth through mediation of apoptosis. Low level expression of P2X(7) has been linked to cancer development because tumor cells harboring a defective P2X(7) mechanism can escape P2X(7) pro-apoptotic control. microRNAs (miRNAs) function as negative regulators of pos...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846619/ https://www.ncbi.nlm.nih.gov/pubmed/24312495 http://dx.doi.org/10.1371/journal.pone.0080707 |