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miR-150 Promotes Human Breast Cancer Growth and Malignant Behavior by Targeting the Pro-Apoptotic Purinergic P2X(7) Receptor

The P2X(7) receptor regulates cell growth through mediation of apoptosis. Low level expression of P2X(7) has been linked to cancer development because tumor cells harboring a defective P2X(7) mechanism can escape P2X(7) pro-apoptotic control. microRNAs (miRNAs) function as negative regulators of pos...

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Detalles Bibliográficos
Autores principales: Huang, Songyin, Chen, Yongsong, Wu, Wei, Ouyang, Nengyong, Chen, Jianing, Li, Hongyu, Liu, Xiaoqiang, Su, Fengxi, Lin, Ling, Yao, Yandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846619/
https://www.ncbi.nlm.nih.gov/pubmed/24312495
http://dx.doi.org/10.1371/journal.pone.0080707