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LPS Exposure Increases Maternal Corticosterone Levels, Causes Placental Injury and Increases IL-1Β Levels in Adult Rat Offspring: Relevance to Autism

Maternal immune activation can induce neuropsychiatric disorders, such as autism and schizophrenia. Previous investigations by our group have shown that prenatal treatment of rats on gestation day 9.5 with lipopolysaccharide (LPS; 100 μg/kg, intraperitoneally), which mimics infections by gram-negati...

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Detalles Bibliográficos
Autores principales: Kirsten, Thiago B., Lippi, Luciana L., Bevilacqua, Estela, Bernardi, Maria M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846733/
https://www.ncbi.nlm.nih.gov/pubmed/24312647
http://dx.doi.org/10.1371/journal.pone.0082244