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MagFRET: The First Genetically Encoded Fluorescent Mg(2+) Sensor

Magnesium has important structural, catalytic and signaling roles in cells, yet few tools exist to image this metal ion in real time and at subcellular resolution. Here we report the first genetically encoded sensor for Mg(2+), MagFRET-1. This sensor is based on the high-affinity Mg(2+) binding doma...

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Detalles Bibliográficos
Autores principales: Lindenburg, Laurens H., Vinkenborg, Jan L., Oortwijn, Jorn, Aper, Stijn J. A., Merkx, Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846734/
https://www.ncbi.nlm.nih.gov/pubmed/24312622
http://dx.doi.org/10.1371/journal.pone.0082009