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MagFRET: The First Genetically Encoded Fluorescent Mg(2+) Sensor
Magnesium has important structural, catalytic and signaling roles in cells, yet few tools exist to image this metal ion in real time and at subcellular resolution. Here we report the first genetically encoded sensor for Mg(2+), MagFRET-1. This sensor is based on the high-affinity Mg(2+) binding doma...
Autores principales: | Lindenburg, Laurens H., Vinkenborg, Jan L., Oortwijn, Jorn, Aper, Stijn J. A., Merkx, Maarten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846734/ https://www.ncbi.nlm.nih.gov/pubmed/24312622 http://dx.doi.org/10.1371/journal.pone.0082009 |
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