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Surfactant Protein A Binds Flagellin Enhancing Phagocytosis and IL-1β Production

Surfactant protein A (SP-A), a pulmonary collectin, plays a role in lung innate immune host defense. In this study the role of SP-A in regulating the inflammatory response to the flagella of Pseudomonas aeruginosa (PA) was examined. Intra-tracheal infection of SP-A deficient (SP-A-/-) C57BL/6 mice w...

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Detalles Bibliográficos
Autores principales: Ketko, Anastasia K., Lin, Chinhong, Moore, Bethany B., LeVine, Ann Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846784/
https://www.ncbi.nlm.nih.gov/pubmed/24312669
http://dx.doi.org/10.1371/journal.pone.0082680