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Surfactant Protein A Binds Flagellin Enhancing Phagocytosis and IL-1β Production
Surfactant protein A (SP-A), a pulmonary collectin, plays a role in lung innate immune host defense. In this study the role of SP-A in regulating the inflammatory response to the flagella of Pseudomonas aeruginosa (PA) was examined. Intra-tracheal infection of SP-A deficient (SP-A-/-) C57BL/6 mice w...
Autores principales: | Ketko, Anastasia K., Lin, Chinhong, Moore, Bethany B., LeVine, Ann Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846784/ https://www.ncbi.nlm.nih.gov/pubmed/24312669 http://dx.doi.org/10.1371/journal.pone.0082680 |
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