Vitamin A Deficiency Impairs Adaptive B and T Cell Responses to a Prototype Monovalent Attenuated Human Rotavirus Vaccine and Virulent Human Rotavirus Challenge in a Gnotobiotic Piglet Model

Rotaviruses (RV) are a major cause of gastroenteritis in children. Widespread vitamin A deficiency is associated with reduced efficacy of vaccines and higher incidence of diarrheal infections in children in developing countries. We established a vitamin A deficient (VAD) gnotobiotic piglet model tha...

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Detalles Bibliográficos
Autores principales: Chattha, Kuldeep S., Kandasamy, Sukumar, Vlasova, Anastasia N., Saif, Linda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846786/
https://www.ncbi.nlm.nih.gov/pubmed/24312675
http://dx.doi.org/10.1371/journal.pone.0082966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846786/
https://www.ncbi.nlm.nih.gov/pubmed/24312675
http://dx.doi.org/10.1371/journal.pone.0082966

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