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BtcA, A Class IA Type III Chaperone, Interacts with the BteA N-Terminal Domain through a Globular/Non-Globular Mechanism

Bordetella pertussis, the etiological agent of “whooping cough” disease, utilizes the type III secretion system (T3SS) to deliver a 69 kDa cytotoxic effector protein, BteA, directly into the host cells. As with other T3SS effectors, prior to its secretion BteA binds BtcA, a 13.9 kDa protein predicte...

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Detalles Bibliográficos
Autores principales: Guttman, Chen, Davidov, Geula, Yahalom, Adi, Shaked, Hadassa, Kolusheva, Sofiya, Bitton, Ronit, Barber-Zucker, Shiran, Chill, Jordan H., Zarivach, Raz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846842/
https://www.ncbi.nlm.nih.gov/pubmed/24312558
http://dx.doi.org/10.1371/journal.pone.0081557