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A polymorphism in the histone deacetylase 1 gene is associated with the response to corticosteroids in asthmatics

BACKGROUND/AIMS: Recent investigations suggest that histone deacetylase 1 (HDAC1) and HDAC2 may be target molecules to predict therapeutic responses to corticosteroids. We evaluated the effects of variation in HDAC1 and HDAC2 on the response to corticosteroids in asthmatics. METHODS: Two single nucl...

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Detalles Bibliográficos
Autores principales: Kim, Min-Hye, Kim, Sae-Hoon, Kim, Yook-Keun, Hong, Soo-Jong, Min, Kyung-Up, Cho, Sang-Heon, Park, Heung-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846997/
https://www.ncbi.nlm.nih.gov/pubmed/24307847
http://dx.doi.org/10.3904/kjim.2013.28.6.708