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Active RHOA favors retention of human hematopoietic stem/progenitor cells in their niche

BACKGROUND: Hematopoietic stem/progenitor cells (HSPCs) maintain the hematopoietic system by balancing their self-renewal and differentiation events. Hematopoietic stem cells also migrate to various sites and interact with their specific microenvironment to maintain the integrity of the system. Rho...

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Detalles Bibliográficos
Autores principales: Jaganathan, Bithiah Grace, Anjos-Afonso, Fernando, Kumar, Atul, Bonnet, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847040/
https://www.ncbi.nlm.nih.gov/pubmed/24024707
http://dx.doi.org/10.1186/1423-0127-20-66