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Role of N-Cadherin cis and trans Interfaces in the Dynamics of Adherens Junctions in Living Cells

Cadherins, Ca(2+)-dependent adhesion molecules, are crucial for cell-cell junctions and remodeling. Cadherins form inter-junctional lattices by the formation of both cis and trans dimers. Here, we directly visualize and quantify the spatiotemporal dynamics of wild-type and dimer mutant N-cadherin in...

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Detalles Bibliográficos
Autores principales: Bunse, Stefanie, Garg, Sakshi, Junek, Stephan, Vogel, Dirk, Ansari, Nariman, Stelzer, Ernst H. K., Schuman, Erin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847041/
https://www.ncbi.nlm.nih.gov/pubmed/24312555
http://dx.doi.org/10.1371/journal.pone.0081517