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Increased B Cell and Cytotoxic NK Cell Proportions and Increased T Cell Responsiveness in Blood of Natalizumab-Treated Multiple Sclerosis Patients

BACKGROUND: Changes in the blood lymphocyte composition probably both mediate and reflect the effects of natalizumab treatment in multiple sclerosis, with implications for treatment benefits and risks. METHODS: A broad panel of markers for lymphocyte populations, including states of activation and c...

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Detalles Bibliográficos
Autores principales: Mellergård, Johan, Edström, Måns, Jenmalm, Maria C., Dahle, Charlotte, Vrethem, Magnus, Ernerudh, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847051/
https://www.ncbi.nlm.nih.gov/pubmed/24312575
http://dx.doi.org/10.1371/journal.pone.0081685