Cargando…

Monoacylglycerols Activate TRPV1 – A Link between Phospholipase C and TRPV1

Phospholipase C-mediated hydrolysis of phosphatidylinositol 4,5-bisphosphate generates diacylglycerol, inositol 1,4,5-trisphosphate and protons, all of which can regulate TRPV1 activity via different mechanisms. Here we explored the possibility that the diacylglycerol metabolites 2-arachidonoylglyce...

Descripción completa

Detalles Bibliográficos
Autores principales: Zygmunt, Peter M., Ermund, Anna, Movahed, Pouya, Andersson, David A., Simonsen, Charlotte, Jönsson, Bo A. G., Blomgren, Anders, Birnir, Bryndis, Bevan, Stuart, Eschalier, Alain, Mallet, Christophe, Gomis, Ana, Högestätt, Edward D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847081/
https://www.ncbi.nlm.nih.gov/pubmed/24312564
http://dx.doi.org/10.1371/journal.pone.0081618