Early Increase and Late Decrease of Purkinje Cell Dendritic Spine Density in Prion-Infected Organotypic Mouse Cerebellar Cultures

Prion diseases are infectious neurodegenerative diseases associated with the accumulation of protease-resistant prion protein, neuronal loss, spongiform change and astrogliosis. In the mouse model, the loss of dendritic spines is one of the earliest pathological changes observed in vivo, occurring 4...

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Detalles Bibliográficos
Autores principales: Campeau, Jody L., Wu, Gengshu, Bell, John R., Rasmussen, Jay, Sim, Valerie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847088/
https://www.ncbi.nlm.nih.gov/pubmed/24312586
http://dx.doi.org/10.1371/journal.pone.0081776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847088/
https://www.ncbi.nlm.nih.gov/pubmed/24312586
http://dx.doi.org/10.1371/journal.pone.0081776

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