Evaluation of two novel tablet formulations of artemether-lumefantrine (Coartem®) for bioequivalence in a randomized, open-label, two-period study

BACKGROUND: Artemether-lumefantrine (Coartem®; AL) is a standard of care for malaria treatment as an oral six-dose regimen, given twice daily over three days with one to four tablets (20/120 mg) per dose, depending on patient body weight. In order to reduce the pill burden at each dose and potential...

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Detalles Bibliográficos
Autores principales: Lefèvre, Gilbert, Bhad, Prafulla, Jain, Jay Prakash, Kalluri, Sampath, Cheng, Yi, Dave, Hardik, Stein, Daniel S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847113/
https://www.ncbi.nlm.nih.gov/pubmed/24010572
http://dx.doi.org/10.1186/1475-2875-12-312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847113/
https://www.ncbi.nlm.nih.gov/pubmed/24010572
http://dx.doi.org/10.1186/1475-2875-12-312

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