Proliferation inhibition and apoptosis induction of imatinib-resistant chronic myeloid leukemia cells via PPP2R5C down-regulation

Despite the success of imatinib and other tyrosine kinase inhibitors (TKIs), chronic myeloid leukemia (CML) remains largely incurable, and a number of CML patients die due to Abl mutation-related drug resistance and blast crisis. The aim of this study was to evaluate proliferation inhibition and apo...

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Detalles Bibliográficos
Autores principales: Shen, Qi, Liu, Sichu, Chen, Yu, Yang, Lijian, Chen, Shaohua, Wu, Xiuli, Li, Bo, Lu, Yuhong, Zhu, Kanger, Li, Yangqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847136/
https://www.ncbi.nlm.nih.gov/pubmed/24004697
http://dx.doi.org/10.1186/1756-8722-6-64

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847136/
https://www.ncbi.nlm.nih.gov/pubmed/24004697
http://dx.doi.org/10.1186/1756-8722-6-64

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