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Effective concentration-based serum pharmacodynamics for antifungal azoles in a murine model of disseminated Candida albicans infection
An assessment of the effective in vivo concentrations of antifungal drugs is important in determining their pharmacodynamics, and therefore, their optimal dosage regimen. Here we establish the effective in vivo concentration-based pharmacodynamics of three azole antifungal drugs (fluconazole, itraco...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Paris
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847280/ https://www.ncbi.nlm.nih.gov/pubmed/23539473 http://dx.doi.org/10.1007/s13318-013-0122-4 |