Nanoparticle-mediated catalase delivery protects human neurons from oxidative stress

Several neurodegenerative diseases and brain injury involve reactive oxygen species and implicate oxidative stress in disease mechanisms. Hydrogen peroxide (H(2)O(2)) formation due to mitochondrial superoxide leakage perpetuates oxidative stress in neuronal injury. Catalase, an H(2)O(2)-degrading en...

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Detalles Bibliográficos
Autores principales: Singhal, A, Morris, V B, Labhasetwar, V, Ghorpade, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847304/
https://www.ncbi.nlm.nih.gov/pubmed/24201802
http://dx.doi.org/10.1038/cddis.2013.362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847304/
https://www.ncbi.nlm.nih.gov/pubmed/24201802
http://dx.doi.org/10.1038/cddis.2013.362

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