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Nanoparticle-mediated catalase delivery protects human neurons from oxidative stress
Several neurodegenerative diseases and brain injury involve reactive oxygen species and implicate oxidative stress in disease mechanisms. Hydrogen peroxide (H(2)O(2)) formation due to mitochondrial superoxide leakage perpetuates oxidative stress in neuronal injury. Catalase, an H(2)O(2)-degrading en...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847304/ https://www.ncbi.nlm.nih.gov/pubmed/24201802 http://dx.doi.org/10.1038/cddis.2013.362 |