CD40-directed scFv-TRAIL fusion proteins induce CD40-restricted tumor cell death and activate dendritic cells

Targeted cancer therapy concepts often aim at the induction of adjuvant antitumor immunity or stimulation of tumor cell apoptosis. There is further evidence that combined application of immune stimulating and tumor apoptosis-inducing compounds elicits a synergistic antitumor effect. Here, we describ...

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Detalles Bibliográficos
Autores principales: El-Mesery, M, Trebing, J, Schäfer, V, Weisenberger, D, Siegmund, D, Wajant, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847307/
https://www.ncbi.nlm.nih.gov/pubmed/24232092
http://dx.doi.org/10.1038/cddis.2013.402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847307/
https://www.ncbi.nlm.nih.gov/pubmed/24232092
http://dx.doi.org/10.1038/cddis.2013.402

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