Bortezomib antagonizes microtubule-interfering drug-induced apoptosis by inhibiting G2/M transition and MCL-1 degradation

Inhibition of the proteasome is considered as a promising strategy to sensitize cancer cells to apoptosis. Recently, we demonstrated that the proteasome inhibitor Bortezomib primes neuroblastoma cells to TRAIL-induced apoptosis. In the present study, we investigated whether Bortezomib increases chem...

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Detalles Bibliográficos
Autores principales: Rapino, F, Naumann, I, Fulda, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847318/
https://www.ncbi.nlm.nih.gov/pubmed/24263099
http://dx.doi.org/10.1038/cddis.2013.440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847318/
https://www.ncbi.nlm.nih.gov/pubmed/24263099
http://dx.doi.org/10.1038/cddis.2013.440

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