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Tanshinone-1 induces tumor cell killing, enhanced by inhibition of secondary activation of signaling networks
Tumor multidrug resistance (MDR) can result from overexpression of drug transporters and deregulation of cellular signaling transduction. New agents and strategies are required for overcoming MDR. Here, we report that tanshinone-1, a bioactive ingredient in traditional Chinese medicine, directly kil...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847321/ https://www.ncbi.nlm.nih.gov/pubmed/24201804 http://dx.doi.org/10.1038/cddis.2013.443 |