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Tanshinone-1 induces tumor cell killing, enhanced by inhibition of secondary activation of signaling networks

Tumor multidrug resistance (MDR) can result from overexpression of drug transporters and deregulation of cellular signaling transduction. New agents and strategies are required for overcoming MDR. Here, we report that tanshinone-1, a bioactive ingredient in traditional Chinese medicine, directly kil...

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Detalles Bibliográficos
Autores principales: Xu, L, Feng, J-M, Li, J-X, Zhu, J-M, Song, S-S, Tong, L-J, Chen, Y, Yang, X-Y, Shen, Y-Y, Lian, F-L, Li, Y-P, Lin, D-H, Ding, J, Miao, Z-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847321/
https://www.ncbi.nlm.nih.gov/pubmed/24201804
http://dx.doi.org/10.1038/cddis.2013.443