Differential regulation of the apoptotic machinery during megakaryocyte differentiation and platelet production by inhibitor of apoptosis protein Livin

Livin is a member of the inhibitor of apoptosis proteins (IAP) family of intracellular antiapoptotic proteins that act by binding and inhibiting caspases. Upon strong apoptotic stimuli, it is then specifically cleaved by caspases to produce a truncated protein (tLivin) with a paradoxical proapoptoti...

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Detalles Bibliográficos
Autores principales: Abd-Elrahman, I, Deutsch, V, Pick, M, Kay, S, Neuman, T, Perlman, R, Ben-Yehuda, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847330/
https://www.ncbi.nlm.nih.gov/pubmed/24287698
http://dx.doi.org/10.1038/cddis.2013.454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847330/
https://www.ncbi.nlm.nih.gov/pubmed/24287698
http://dx.doi.org/10.1038/cddis.2013.454

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