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Differential regulation of the apoptotic machinery during megakaryocyte differentiation and platelet production by inhibitor of apoptosis protein Livin
Livin is a member of the inhibitor of apoptosis proteins (IAP) family of intracellular antiapoptotic proteins that act by binding and inhibiting caspases. Upon strong apoptotic stimuli, it is then specifically cleaved by caspases to produce a truncated protein (tLivin) with a paradoxical proapoptoti...
Autores principales: | Abd-Elrahman, I, Deutsch, V, Pick, M, Kay, S, Neuman, T, Perlman, R, Ben-Yehuda, D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847330/ https://www.ncbi.nlm.nih.gov/pubmed/24287698 http://dx.doi.org/10.1038/cddis.2013.454 |
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