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TLR9 signaling repressed tumor suppressor miR-7 expression through up-regulation of HuR in human lung cancer cells

BACKGROUND: Our recent evidence showed that Toll like receptor 9 (TLR9) signaling could enhance the growth and metastatic potential of human lung cancer cells through repressing microRNA-7 (miR-7) expression. Human antigen R (HuR) has been involved in stabilizing multiple mRNAs in cellular biology....

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Detalles Bibliográficos
Autores principales: Li, Yong-Ju, Wang, Chun-Hong, Zhou, Ya, Liao, Zheng-Yuan, Zhu, Shun-Fei, Hu, Yan, Chen, Chao, Luo, Jun-Min, Wen, Zhen-Ke, Xu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847485/
https://www.ncbi.nlm.nih.gov/pubmed/24004462
http://dx.doi.org/10.1186/1475-2867-13-90