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Maximum-parsimony haplotype frequencies inference based on a joint constrained sparse representation of pooled DNA
BACKGROUND: DNA pooling constitutes a cost effective alternative in genome wide association studies. In DNA pooling, equimolar amounts of DNA from different individuals are mixed into one sample and the frequency of each allele in each position is observed in a single genotype experiment. The identi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847492/ https://www.ncbi.nlm.nih.gov/pubmed/24010487 http://dx.doi.org/10.1186/1471-2105-14-270 |