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Maximum-parsimony haplotype frequencies inference based on a joint constrained sparse representation of pooled DNA

BACKGROUND: DNA pooling constitutes a cost effective alternative in genome wide association studies. In DNA pooling, equimolar amounts of DNA from different individuals are mixed into one sample and the frequency of each allele in each position is observed in a single genotype experiment. The identi...

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Detalles Bibliográficos
Autores principales: Jajamovich, Guido H, Iliadis, Alexandros, Anastassiou, Dimitris, Wang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847492/
https://www.ncbi.nlm.nih.gov/pubmed/24010487
http://dx.doi.org/10.1186/1471-2105-14-270