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Whiskers-less HIV-protease: a possible way for HIV-1 deactivation

BACKGROUND: Among viral enzymes, the human HIV-1 protease comprises the most interesting target for drug discovery. There are increasing efforts focused on designing more effective inhibitors for HIV-1 protease in order to prevent viral replication in AIDS patients. The frequent and continuous mutat...

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Detalles Bibliográficos
Autores principales: Dayer, Mohammad Reza, Dayer, Mohammad Saaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847613/
https://www.ncbi.nlm.nih.gov/pubmed/24024748
http://dx.doi.org/10.1186/1423-0127-20-67