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A valid strategy for precise identifications of transcription factor binding sites in combinatorial regulation using bioinformatic and experimental approaches

BACKGROUND: Transcription factor (TF) binding sites (cis element) play a central role in gene regulation, and eukaryotic organisms frequently adapt a combinatorial regulation to render sophisticated local gene expression patterns. Knowing the precise cis element on a distal promoter is a prerequisit...

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Detalles Bibliográficos
Autores principales: Wang, Hailong, Guan, Shan, Zhu, Zhixin, Wang, Yan, Lu, Yingqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847620/
https://www.ncbi.nlm.nih.gov/pubmed/23971995
http://dx.doi.org/10.1186/1746-4811-9-34