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Sigma-1 receptor expression in sensory neurons and the effect of painful peripheral nerve injury

BACKGROUND: The sigma-1 receptor (σ1R), an endoplasmic reticulum chaperone protein, is widely distributed and regulates numerous intracellular processes in neurons. Nerve injury alters the structure and function of axotomized dorsal root ganglion (DRG) neurons, contributing to the development of pai...

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Detalles Bibliográficos
Autores principales: Bangaru, Madhavi L, Weihrauch, Dorothee, Tang, Qing-Bo, Zoga, Vasiliki, Hogan, Quinn, Wu, Hsiang-en
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847629/
https://www.ncbi.nlm.nih.gov/pubmed/24015960
http://dx.doi.org/10.1186/1744-8069-9-47