Cargando…

VprBP (DCAF1): a promiscuous substrate recognition subunit that incorporates into both RING-family CRL4 and HECT-family EDD/UBR5 E3 ubiquitin ligases

The terminal step in the ubiquitin modification system relies on an E3 ubiquitin ligase to facilitate transfer of ubiquitin to a protein substrate. The substrate recognition and ubiquitin transfer activities of the E3 ligase may be mediated by a single polypeptide or may rely on separate subunits. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakagawa, Tadashi, Mondal, Koushik, Swanson, Patrick C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847654/
https://www.ncbi.nlm.nih.gov/pubmed/24028781
http://dx.doi.org/10.1186/1471-2199-14-22