Cargando…

DC-SIGN gene promoter variants and IVIG treatment response in Kawasaki disease

BACKGROUND: Genetic variants in the inhibiting FcγRIIB mediate anti-inflammatory responses and influence IVIG refractoriness (IVIG-R). However, these variants are rare in Asian and Hispanic populations so other genes in the pathway could be potentially involved. IVIG is ineffective in mice lacking S...

Descripción completa

Detalles Bibliográficos
Autores principales: Portman, Michael A, Wiener, Howard W, Silva, Miriam, Shendre, Aditi, Shrestha, Sadeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847673/
https://www.ncbi.nlm.nih.gov/pubmed/24006904
http://dx.doi.org/10.1186/1546-0096-11-32