An EM algorithm based on an internal list for estimating haplotype distributions of rare variants from pooled genotype data

BACKGROUND: Pooling is a cost effective way to collect data for genetic association studies, particularly for rare genetic variants. It is of interest to estimate the haplotype frequencies, which contain more information than single locus statistics. By viewing the pooled genotype data as incomplete...

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Detalles Bibliográficos
Autores principales: Kuk, Anthony YC, Li, Xiang, Xu, Jinfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847674/
https://www.ncbi.nlm.nih.gov/pubmed/24034507
http://dx.doi.org/10.1186/1471-2156-14-82

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847674/
https://www.ncbi.nlm.nih.gov/pubmed/24034507
http://dx.doi.org/10.1186/1471-2156-14-82

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