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Disclosing the crosstalk among DNA methylation, transcription factors, and histone marks in human pluripotent cells through discovery of DNA methylation motifs

Gene expression regulation is gated by promoter methylation states modulating transcription factor binding. The known DNA methylation/unmethylation mechanisms are sequence unspecific, but different cells with the same genome have different methylomes. Thus, additional processes bringing specificity...

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Detalles Bibliográficos
Autores principales: Luu, Phuc-Loi, Schöler, Hans R., Araúzo-Bravo, Marcos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847772/
https://www.ncbi.nlm.nih.gov/pubmed/24149073
http://dx.doi.org/10.1101/gr.155960.113