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Analysis of variable retroduplications in human populations suggests coupling of retrotransposition to cell division

In primates and other animals, reverse transcription of mRNA followed by genomic integration creates retroduplications. Expressed retroduplications are either “retrogenes” coding for functioning proteins, or expressed “processed pseudogenes,” which can function as noncoding RNAs. To date, little is...

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Detalles Bibliográficos
Autores principales: Abyzov, Alexej, Iskow, Rebecca, Gokcumen, Omer, Radke, David W., Balasubramanian, Suganthi, Pei, Baikang, Habegger, Lukas, Lee, Charles, Gerstein, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847774/
https://www.ncbi.nlm.nih.gov/pubmed/24026178
http://dx.doi.org/10.1101/gr.154625.113