Distinct global shifts in genomic binding profiles of limb malformation-associated HOXD13 mutations

Gene regulation by transcription factors (TFs) determines developmental programs and cell identity. Consequently, mutations in TFs can lead to dramatic phenotypes in humans by disrupting gene regulation. To date, the molecular mechanisms that actually cause these phenotypes have been difficult to ad...

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Detalles Bibliográficos
Autores principales: Ibrahim, Daniel M., Hansen, Peter, Rödelsperger, Christian, Stiege, Asita C., Doelken, Sandra C., Horn, Denise, Jäger, Marten, Janetzki, Catrin, Krawitz, Peter, Leschik, Gundula, Wagner, Florian, Scheuer, Till, Schmidt-von Kegler, Mareen, Seemann, Petra, Timmermann, Bernd, Robinson, Peter N., Mundlos, Stefan, Hecht, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847778/
https://www.ncbi.nlm.nih.gov/pubmed/23995701
http://dx.doi.org/10.1101/gr.157610.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847778/
https://www.ncbi.nlm.nih.gov/pubmed/23995701
http://dx.doi.org/10.1101/gr.157610.113

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