Single-cell methylome landscapes of mouse embryonic stem cells and early embryos analyzed using reduced representation bisulfite sequencing

DNA methylation is crucial for a wide variety of biological processes, yet no technique suitable for the methylome analysis of DNA methylation at single-cell resolution is available. Here, we describe a methylome analysis technique that enables single-cell and single-base resolution DNA methylation...

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Detalles Bibliográficos
Autores principales: Guo, Hongshan, Zhu, Ping, Wu, Xinglong, Li, Xianlong, Wen, Lu, Tang, Fuchou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847781/
https://www.ncbi.nlm.nih.gov/pubmed/24179143
http://dx.doi.org/10.1101/gr.161679.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847781/
https://www.ncbi.nlm.nih.gov/pubmed/24179143
http://dx.doi.org/10.1101/gr.161679.113

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